General Genetics Lab (GB 426)
Fall 2018

instructor: Dwight Moore, Ph.D.
office - Science Hall 144
phone - 620-341-5611
email -    (put "genetics" in the subject line)

office hours:   Monday, Wednesday, and Friday 9:00 - 10:00; Monday 1:00 - 2:00; and by appointment. If I am in my office and not already talking with another person, feel free to stop in.    my schedule

section:GB 426, Monday 2:00 - 3:50, Science Hall 158

text:Drosophila (required). This is free software at

Lab handouts that I will give you plus your lecture textbook, Pierce, B. A. 2016. Genetics: A conceptual approach. 6th edition. W. H. Freeman and Company.

I. course description:

Genetics lab is a course designed for biology majors. The objectives of the course are to allow hands on work that will illustrate principles that are presented in the lecture course (GB 425) and to provide an opportunity for the presentation of scientific results and theories.

II. prerequisites:

You must have completed a general or introductory biology course and a college algebra course with a C or better in both. The biology course will have given you the basics of the terminology and major theories in biology. The college algebra course will have given you the tools to manipulate mathematical equations that you need to understand genetics.

III. course organization:

Material will be presented in the form of lectures, reading assignments and handouts. The class will require that you come to lab or work on a computer outside of the regularly scheduled class periods to complete experiments.

IV. grading:

Your grade will be based 35% on your study questions over the lab work, 25% on the one paper from your class project, and 40% on the examinations. There will be lab questions to be turned in for most labs, 3 examinations during the semester, and one paper from the class project.
A  = 92.0% to 100%
A-  = 89.0% to 91.9%
B+  = 86.0% to 88.9%
B  = 83.0% to 85.9%
B-  = 79.0% to 82.9%
C+  = 76.0% to 78.9%
C  = 70.0% to 75.9%
D  = 60.0% to 69.9%
F < 60.0%

Your lab work will be graded based upon your answers to the questions at the end of the lab exercises and your interpretation of your data. Study questions are due at the beginning of the next lab period, unless stated otherwise, and will NOT be accepted late.

The paper will be a collarborative project that involves two or three students per group. The paper that results from this project will be due during finals week. Each group will turn in one paper and each student within a group will receive the essentially the same grade with some minor flexibility. Plagiarizing your paper from some other source or collaborative efforts with other students outside your group will be considered cheating and will result in a grade of zero for your efforts for all students in the group. See the information on plagiarism and quotes in the "Instructions for Review Papers in Genetics". The paper must be in the form of a scientific paper. The purpose is to introduce you to the style and format followed by scientists in reporting research. In addition, a written report helps to crystallize your thoughts on a particular subject. The lab write-up is expected to have a clear introduction to the exercise, a presentation of the methods and results, and a complete discussion that shows that you understand the lab exercise and its implications to genetics. See the handout on lab write-ups. It must be typewritten and double-spaced, and include five citations, which are cited in the text and listed in the literature cited. The lab write-up will also be graded on consistency of style, grammar, clarity, and freedom from typographical errors.

Papers are due in my mailbox by 4:00 pm on 14 December 2017. A 5-POINT PENALTY WILL BE ASSESSED IF IT IS TURNED IN LATE. Your collective group is responsible for turning in the paper. Late penalty points will be assessed against all students in the group. In addition, another 5-point penalty will be assessed for every day that the paper is late, and of course days during holidays and weekends count as days late.

There will be three lab exams scheduled during the semester, see the lab schedule. The exams will be given at the beginning of lab and they may vary in points-possible on each exam. The exams will only cover the material covered since the previous test.

V. academic dishonesty:

Plagiarism, which was mentioned above and is described in more detail in the "Instructions for Review Papers in Genetics" will result in a zero on your term paper. Any copying or other forms of cheating during a test will result in a zero on that exam. The Chair of the Department of Biological Sciences will be informed of all acts of academic dishonesty and the action taken against the offender. In addition, your name will be placed on a list in the Office of the Vice President for Academic Affairs. Be sure to review the Policies on Academic Dishonesty of the Department of Biological Sciences and of Emporia State University.

VI. accommodations for disabilities:

Emporia State University will make reasonable accommodations for persons with documented disabilities. Students need to contact the Director of Disability Services (Plumb Hall 106, 341-6637) and the professor as early in the semester as possible to ensure that classroom and academic accommodations are implemented in a timely fashion. All communication among the student, the Office of Disability Services, and the professor will be strictly confidential.

VII. statement on diveresity/inclusivity:

Emporia State University supports an inclusive learning environment where diversity and individual differences are understood, respected, appreciated, and recognized as a source of strength. We expect that students and faculty at Emporia State will respect differences and demonstrate diligence in understanding how other people’s perspectives, behaviors, and worldviews may be different from their own. If there are aspects of the design, instruction, and/or your experiences within this course that result in barriers to your inclusion or accurate assessment of achievement, please notify the unit head (Department Chair or equivalent) as soon as possible, and/or contact the office of the Assistant Dean of Students for Diversity, Equity & Inclusion.

VIII. important and useful information from the registrar.


In general, material in lab will have already been covered in lecture. I will expect you to have learned the relevant material from lecture before coming to lab. I will not cover this material again in lab. I will, however, often present new material in lab. Thus, it is important that you attend all labs.

20 Aug a) introduction
b) organization of a scientific paper
c) mitosis, meiosis (slides)
27 Auga) monohybrid cross using corn
b) dihybrid cross using corn
c) crosses using the Drosophila website
3 SepNo Class, Labor Day
10 Sep a) statistics, chi-square analysis
b) crosses using the Drosophila website
17 Sep a) exam #1 (organization of a scientific paper, monohybrid cross, mitosis, meiosis, chi-square labs)

b) genes linked on a chromosome in corn (two point cross)
24 Sep a) X-chromosome inactivation (Barr bodies)
b) crosses using the Drosophila website
1 Octa) karyology, examination of human chromosomes
b) technique for obtaining chromosome preparations
8 Octa) Hardy-Weinberg equilibrium
15 Octa) genome organization, Microbial Genetics Database
22 Octa) exam #2 (dihybrid cross, Barr bodies, karyology, linkage in corn, Hardy-Weinberg Equilibrium)
29 Octa) genome organization, Microbial Genetics Database
5 Nova) computer simulations of models in population genetics
12 NovNo Class, Veterans Day
19 Nova)linkage
26 Novmeasuring genetic variation
3 Deca) exam #3 (Hardy-Weinberg, gel electrophoresis, computer simulations, TIGR database)
12 Deca) lab paper due in my mailbox by 4:00 pm, topic to be announced

Provide comments to Dwight Moore at
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